Wednesday, January 16, 2008

Technological Evolution Vs. Biological Evolution

This is just a quick example of how technologically things are getting smarter and smarter as they get smaller and smaller, the opposite of our biological evolution from which all of our technological evolution has evolved.

Jobs Reveals Tiny New Laptop
Jan 15 02:29 PM US/Eastern
By MAY WONG and JORDAN ROBERTSON
AP Technology Writers


Ultra-Lightweight, .76 Inch-Thick Apple Notebook ‘MacBook Air’ Unveiled

SAN FRANCISCO (AP) - Apple Inc. Chief Executive Steve Jobs took the wraps off a super-slim new laptop at Macworld Tuesday, unveiling a personal computer less than an inch thick that turns on the moment it's opened.

Jobs also confirmed the tech giant's foray into online movie rentals, revealing an alliance with all six major movie studios to offer films over high-speed Internet connections 30 days after they're released on DVD.

Always a showman, Jobs unwound the string on a standard-sized manila office envelope and slid out the ultra-thin MacBook Air notebook computer to coos and peals of laughter from fans at the conference.

At its beefiest, the new computer is .76 inches thick; at its thinnest, it's .16 inches, he said. It comes standard with an 80- gigabyte hard drive, with the option of a 64GB flash-based solid state drive as an upgrade.

Monday, January 14, 2008

Texas UFO

Dozens in Texas town report seeing UFO

By ANGELA K. BROWN, Associated Press Writer 2 hours, 58 minutes ago

STEPHENVILLE, Texas - In this farming community where nightfall usually brings clear, starry skies, residents are abuzz over reported sightings of what many believe is a UFO.
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Several dozen people — including a pilot, county constable and business owners — insist they have seen a large silent object with bright lights flying low and fast. Some reported seeing fighter jets chasing it.

"People wonder what in the world it is because this is the Bible Belt, and everyone is afraid it's the end of times," said Steve Allen, a freight company owner and pilot who said the object he saw last week was a mile long and half a mile wide. "It was positively, absolutely nothing from these parts."

While federal officials insist there's a logical explanation, locals swear that it was larger, quieter, faster and lower to the ground than an airplane. They also said the object's lights changed configuration, unlike those of a plane. People in several towns who reported seeing it over several weeks have offered similar descriptions of the object.

Machinist Ricky Sorrells said friends made fun of him when he told them he saw a flat, metallic object hovering about 300 feet over a pasture behind his Dublin home. But he decided to come forward after reading similar accounts in the Stephenville Empire-Tribune.

"You hear about big bass or big buck in the area, but this is a different deal," Sorrells said. "It feels good to hear that other people saw something, because that means I'm not crazy."

Sorrells said he has seen the object several times. He said he watched it through his rifle's telescopic lens and described it as very large and without seams, nuts or bolts.

Maj. Karl Lewis, a spokesman for the 301st Fighter Wing at the Joint Reserve Base Naval Air Station in Fort Worth, said no F-16s or other aircraft from his base were in the area the night of Jan. 8, when most people reported the sighting.

Lewis said the object may have been an illusion caused by two commercial airplanes. Lights from the aircraft would seem unusually bright and may appear orange from the setting sun.

"I'm 90 percent sure this was an airliner," Lewis said. "With the sun's angle, it can play tricks on you."

Officials at the region's two Air Force bases — Dyess in Abilene and Sheppard in Wichita Falls — also said none of their aircraft were in the area last week. The Air Force no longer investigates UFOs.

One man has offered a reward for a photograph or videotape of the mysterious object.

About 200 UFO sightings are reported each month, mostly in California, Colorado and Texas, according to the Mutual UFO Network, which plans to go to the 17,000-resident town of Stephenville to investigate.

Fourteen percent of Americans polled last year by The Associated Press and Ipsos say they have seen a UFO.

Erath County Constable Lee Roy Gaitan said that he first saw red glowing lights and then white flashing lights moving fast, but that even with binoculars could not see the object to which the lights were attached.

"I didn't see a flying saucer and I don't know what it was, but it wasn't an airplane, and I've never seen anything like it," Gaitan said. "I think it must be some kind of military craft — at least I hope it was."

Sunday, January 13, 2008

Bioartificial Heart Signals Potential For More Organs

First bioartificial heart may signal end of organ shortage

Last Updated: 11:01am GMT 13/01/2008

Breakthrough which marks the creation of the first living artificial heart could signal the beginning of the end of organ shortages, reports Roger Highfield

Doctors have stripped down and refurbished a dead heart so that it can beat again, an unprecedented feat that could signal the beginning of the end of organ shortages..

Scientists in Minnesota grow a heart
Watch: Scientists in Minnesota grow a heart

The revolutionary research could overcome the shortage of replacement hearts and other organs, and do away with the need for antirejection drugs, according to an American team.

The world's first beating, retooled "bioartificial heart" is described today in the journal Nature Medicine by University of Minnesota researchers in research that could pave the way to a new treatment for the 22 million people worldwide who live with heart failure.

The team took a whole heart and removed cells from it. Then, with the resulting architecture, chambers, valves and the blood vessel structure intact, repopulated the structure with new cells.

"We just took nature's own building blocks to build a new organ," says Dr Harald Ott, a co-investigator who now works at Massachusetts General Hospital. "When we saw the first contractions we were speechless."
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The work has huge implications: "The idea would be to develop transplantable blood vessels or whole organs that are made from your own cells," said Prof Doris Taylor, director of the Centre for Cardiovascular Repair, Minnesota, principal investigator.

The method could be used to grow liver, kidney, lung and pancreas, indeed virtually any organ with a blood supply.

She tells The Daily Telegraph that although "years away" from using the method in hospitals, she is ready to grow a human heart, though costs make it prohibitive at present.

"We could begin with human cells and pig or human scaffold now but creating the larger bioreactors (the vessels in which the organs are grown) and generating the reagents and growing enough cells would cost tens of thousands of dollars for each heart at this point.

"That is just too expensive to answer basic questions. We of course want to move in that direction, but funding is limited. As we can we will go forward - perhaps one heart at a time. "

In general, the supply of donor organs is limited and once a heart is transplanted, individuals face life-long immunosuppression, where drugs are used to prevent rejection, often trading heart failure for high blood pressure, diabetes, and kidney failure over the long term..

Because a new heart created by decellularization could be filled with the recipient's own stem cells the researchers believe it's much less likely to be rejected by the body.

And once placed in the recipient, in theory the heart would be nourished, regulated, and regenerated similar to the heart that it replaced.

"We used immature heart cells in this version, as a proof of concept. We pretty much figured heart cells in a heart matrix had to work," Prof Taylor says. "Going forward, our goal is to use a patient's stem cells to build a new heart."

As for the source of the cells from a heart patient, she says: "From muscle, bone marrow, or heart; depending on where the science leads us."

Although heart repair was the initial goal, decellularization shows potential to change how scientists think about engineering any organ, she says. "It opens a door to this notion that you can make any organ: kidney, liver, lung, pancreas - you name it and we hope we can make it."

UK Transplant comments that 155 people had their lives saved or transformed by a heart transplant last year, though 28 died while on the waiting list. Currently, 81 people are waiting for heart transplant.

Nationally, more than 9,000 people need a transplant, yet typically only around 3,000 are performed every year. Last year 1,000 people died needing a transplant. A UK Transplant spokesman says: "These developments offer long term hope and long may they continue but the real problem now is a desperate shortage of donated hearts."

Dr Tim Chico, Consultant Cardiologist, University of Sheffield, says: "This is an ingenious step towards solving a massive problem. Heart failure (an inability of the heart to pump sufficient blood, usually after a heart attack) is increasing in the UK.

"A chronic shortage of donors for heart transplantation makes stem cell therapy appealing. The study is very preliminary, but it does show that stem cells can regrow in the 'skeleton' of a donor heart. However, it will take a lot of further work to assess whether this will ever be a viable option for patients."

"This very exciting study," comments Dr Jon Frampton, University of Birmingham. "Although this is only a first step requiring considerable follow-up development, the study nevertheless represents an exciting breakthrough that will eventually make the prospect of repairing damaged hearts a reality and will also be an approach that can be extended to other organs."

Prof Wayne Morrison, Director of the Bernard O'Brien Institute of Microsurgery, Melbourne, comments: "This is the first time a whole organ has been tissue engineered outside the body.

"They have demonstrated that they can create a heart that looks like a heart and is shaped like a heart and, most excitingly, that they can re-establish the blood vessels that were originally there. It is this 'regrowth' of the blood vessel cells that gives the potential in the future to connect this structure to a blood vessel in the body and then get circulation to go through it.

Dr Anita Thomas at the Australian Institute for Bioengineering and Nanotechnology, University of Queensland, adds: "There is one more major step to achieve before we can proceed any further: we need to see what happens when these artificial hearts are placed in a recipient animal for any length of time. The authors of the article have the necessary skills and yet have not reported their results. We wait with anticipation for their next publication."

How to grow a heart

While there have been advances in growing heart tissue in the lab, the problem has been how to create a 3D scaffold that mimics the complex architecture and intricacies of the body's primary pump.

That is why Prof Doris Taylor and her colleagues resorted to "decellularization" - removing all of the cells from an organ with detergent - in this case an animal cadaver heart - leaving only the extracellular matrix, the framework between the cells, intact, along with the plumbing and heart valves.

After successfully removing all of the cells from both rat and pig hearts, the researchers injected rat hearts with a mixture of immature cells that came from newborn rat hearts and placed the structure in a sterile chamber in the lab to grow.

The results were very promising, Prof Taylor said. Four days after seeding the decellularized heart scaffolds with cells, contractions were observed. Eight days later, the hearts were pumping, albeit at only two per cent of the efficiency of an adult heart.

A study at of the hearts at the cellular level revealed that the "cells have many of the markers we associate with the heart and seem to know how to behave like heart tissue."

Wednesday, December 26, 2007

Stem Cell Breakthrough 2007

2007 stem cell breakthrough is like turning lead into gold

Dec 26 02:35 PM US/Eastern
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It was the kind of breakthrough scientists had dreamed of for decades and its promise to help cure disease appears to be fast on the way to being realized.
Researchers in November announced they were able to turn the clock back on skin cells and transform them into stem cells, the mutable building blocks of organs and tissues.

Then just earlier this month a different team announced it had cured sickle cell anemia in mice using stem cells derived from adult mouse skin.

"This is truly the Holy Grail: To be able to take a few cells from a patient -- say a cheek swab or few skin cells -- and turn them into stem cells in the laboratory," said Robert Lanza, a stem cell pioneer at Advanced Cell Technology.

"This work represents a tremendous scientific milestone - the biological equivalent of the Wright Brothers' first airplane," he told AFP.

"It's bit like learning how to turn lead into gold."

Stem cells offer enormous potential for curing and treating disease because they can be transformed into any cell in the body and then hopefully used to replace damaged or diseased cells, tissues and organs.

But stem cell research has been highly controversial because -- until now -- viable embryos had to be destroyed to extract the stem cells.

US President George W. Bush has banned all federal funding for research on human embryonic stem cells and access to stem cells in other countries has also been restricted because of the difficulty in finding women willing to donate their eggs.

The new technique, while far from perfected, is so promising that the man who managed to clone the world's first sheep, Dolly, is giving up his work cloning embryos to focus on studying stem cells derived from skin cells.

"The fact that (the) introduction of a small number of proteins into adult human cells could produce cells that are equivalent to embryo stem cells takes us into an entirely new era of stem cell biology," said Ian Wilmut, the Scottish researcher who first created a viable clone by transferring a cell nucleus into a new embryo.

One of the greatest advantages of the new technique is its simplicity: it takes just four genes to turn the skin cell back into a stem cell.

This, unlike the complex and expensive process developed by Wilmut, can be done in a standard biological lab. And skin cells are much easier to harvest than embryos.

"It's an explosion of resources," said Konrad Hochedlinger, of the Harvard Stem Cell Institute.

Prior to this discovery, researchers who wanted to look at how diseases developed would usually have to study animals or organs harvested from cadavers because embryonic stem cells were so hard to use and access.

But with stem cells derived from skin, tissues and organs can be grown in a petri dish, making it easier for researchers to map the genetic structure of diseased cells, a process which could unlock a cure.

They could also allow researchers to do chemical screens to identify drugs which may cure or treat a disease, a process which could significantly speed up the process of bringing life-saving drugs to the market.

The use of skin cells will eventually allow doctors to create stem cells with a specific patient's genetic code, eliminating the risk that the body would reject transplanted tissues or organs.

Researchers have already shown this is possible when they cured sickle cell anemia in mice.

They used skin cells taken from the tails of sick mice, transformed them into stem cells, manipulated those stem cells into healthy bone marrow cells and then transplanted them into the sick mice.

And since the new cells came from the sick mice, there was also no need for dangerous immunosuppressant drugs to prevent rejection.

But leading stem cell researchers warned that the skin cells are not yet -- and might never be -- a substitute for embryonic stem cells.

"This new research is just the beginning -- we hardly understand how these cells work," said James Thomson of the University of Wisconsin at Madison, who led one of the two teams which made the simultaneous discoveries.

"It is not the time to abandon stem cell research," Thomson said, adding that embryonic stem cells will remain the "gold standard" by which other research is measured.

Further research is also needed to find a safer way to transform the skin cells and to make sure that the cells do not deteriorate over time.


Copyright AFP 2007, AFP stories and photos shall not be published, broadcast, rewritten for broadcast or publication or redistributed directly or indirectly in any medium

Monday, December 24, 2007

British Government - Release of UFO Files

Britain set to release secret UFO files


Published: Dec. 23, 2007 at 4:24 PM
Print story Email to a friend Font size:LONDON, Dec. 23 (UPI) -- The British government will soon release previously classified details regarding hundreds of reported sightings of unidentified flying objects.

The Sunday Telegraph said Sunday that this coming spring, the Defense Ministry will release to the general public 160 files about alleged UFO sightings.

Since the British government department began keeping records about the unusual reports in 1950, more than 10,000 sightings have been recorded.

With officials failing to explain 5 percent of those sightings, a growing number of Freedom of Information requests prompted the release of the classified information.

A former head of the Defense Ministry UFO project told the newspaper that no matter what an individual believes regarding UFOs, the released files should prove to be interesting reading.

"Whatever people think about UFOs, these documents are fascinating and show how the MoD has researched and investigated this mystery for nearly 60 years, without an answer," former department official Nick Pope said.


© 2007 United Press International. All Rights Reserved.
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Thursday, November 29, 2007

UFO Encounter

Today 11-29-07, I had a meeting with a housing consultant who brought along her friend who is the wife of an engineer I know. During lunch we were talking about the book and when I got to the part about the extraterrestrials her friend Beth said that she could validate what I was saying. Of course that was a bit of a surprise. She then explained that 4 years ago, she and 16 year old her daughter were traveling in South Carolina on I-95 near State Rd. 301 near Shaw AFB. They were returning from a horse show. The trainer along with another woman and two children were in a truck towing 6 horses in trailer ahead of them. It was dark when Beth's daughter told her mother to look up. In front of them was a strange large cloud. As they continued closer, there were two very bright flashes of light. They noticed that cars were pulling off of the road on both sides. Once under the cloud there was an enormous triangular UFO craft with fuselages under the wings. It was so large that it spanned the Interstate and part of the woods. It was totally silent with no lights. She kept looking away from it, trying to grasp what she was viewing. She remembered curved windows spanning the second story which looked to be the control center and having the feeling that they were being watched. Then a loud buzzing sound started in their car and she was yelling to her daughter that she didn't break her cell phone because it wouldn't work. After several minutes, the UFO craft glided over the car and she saw a box shaped area on the underside. It then went west and disappeared into the woods. They all got off at the next exit and pulled into a convenient store parking lot. As they exited their vehicles, there was a woman standing alone and screaming hysterically. They simply couldn't believe what they had just seen. She got $10 worth of gas and got home as quickly as possible. It was witnessed by a number of individuals.

Thursday, November 22, 2007

Book is Available! Amazing Contact

The book is now available on the net. My friend Gerry Kurth found another book by another Tom Crawford but along similar lines. I checked it out and it's new and will be available soon. The most amazing thing is that this Tom Crawford is a scientist and his book The Conscious Universe is about physics and our universal connection. I made contact with him yesterday through his publisher and he's absolutely amazed about our connection through our books. None of us understand how the inspirational/mental/spiritual nexus works but it does! We both also like flying. Anyone buying my book should also get his.